Ms. Reham Badr Nasser, a faculty member at the College of Pharmacy, Al-Zahraa University for Women, has achieved a significant scientific milestone by publishing her research titled:
"Apoptosis induction and enhanced CASP9 expression in liver cancer cells by crocin-conjugated magnetite iron"
in the international journal Heliyon. The journal is indexed within Scopus and Clarivate databases and is ranked within the First Quartile (Q1).
The research investigated the therapeutic effects of Iron Oxide Nanoparticles ($Fe_3O_4$ NPs) conjugated with crocin in combating Hepatocellular carcinoma. The results demonstrated that these nanoparticles possess promising efficacy in inhibiting cancer cell growth by inducing apoptosis (programmed cell death) and enhancing the expression of the CASP9 gene, which is closely linked to cellular apoptotic pathways.
The study's findings suggest the potential for utilizing these nanoparticles as an effective nano-drug delivery system for treating liver cancer. This opens new horizons for developing innovative therapeutic strategies based on nanotechnology in the medical field.
This achievement falls within the efforts of the College of Pharmacy at Al-Zahraa University for Women to support scientific research and enhance knowledge production in biotechnology and medical nanotechnology. Such contributions ensure alignment with global scientific advancements and provide innovative therapeutic solutions for incurable diseases.
