Lect. Dr. Dhia’ Rahim Al-Tamimi, Pharmacy Faculty member at Al-Zahraa University for Women, has published a scientific study in the Journal of Shahrekord University of Medical Sciences, focusing on the antiviral effects of curcumin-loaded selenium nanoparticles against Herpes Simplex Virus Type 1 (HSV-1), one of the most prevalent and contagious human viruses. The study addresses the poor solubility of curcumin, a compound recognized for its antiviral properties, which has a significant impact on clinical efficacy. Additionally, to tackle this issue, the researcher developed an innovative nanosystem utilizing selenium nanoparticles (SeNPs) coated with folic acid and chitosan, which greatly enhances curcumin’s ability to combat the virus. The findings demonstrate that incorporating curcumin into SeNPs substantially increased its antiviral potency against HSV-1, even at lower concentrations. It is noteworthy that this advancement opens up new avenues for therapeutic applications, allowing for the use of reduced drug doses, which could minimize potential side effects and optimize treatment efficacy. Translated by Zahra' Ala', revised by Asst. Lect. Inam Mohammed